Genymotion Desktop does not work since I upgraded to macOs Big Sur 11.0.1

If you get the error message Failed to create Vbox host-only interface after upgrading macOs to Big Sur, you may need to follow these instructions:

Method 1

1. Remove VirtualBox with the VirtualBox_uninstall.tool from the official VirtualBox dmg installer, from a rooted terminal
2. Install VirtualBox 6.1.20. The installer for macOs can be found at https://download.virtualbox.org/virtualbox/6.1.20/VirtualBox-6.1.20-143896-OSX.dmg
3. Reboot macOS. It is mandatory to reboot, otherwise VirtualBox will not be operational

Method 2

If this still doesn't work, try these:

1. Boot to recovery (cmd+R) and use these commands:
   csrutil clear
reboot
2. Uninstall VirtualBox and install VirtualBox 6.1.20
3. Go to System Preferences - Privacy - General to authorize the installation of VirtualBox kernel modules.

Method 3

If none of the previous methods worked, try this one:

1. Uninstall VirtualBox with the uninstall tool found in the dmg (VirtualBox_uninstall.tool)
2. Restore SIP to default: sudo csrutil clear
3. Reboot
4. Clear staging: sudo kextcache --clear-staging
5. Reboot
6. Install VirtualBox 6.1.20 and follow system prompt to allow Oracle

Method 4

If none of the above works, some user have reported that installing/updating xcode fixes the issue. For more information about xcode, see https://developer.apple.com/support/xcode/