Your firewall is restrictive
If you have a firewall, make sure that connections for local network 192.168.56.0/24 are allowed. For more information, see Genymotion Desktop and firewalls
You use a VPN or Global Protect
If you have a VPN, make sure that connections for local network 192.168.56.0/24 are not redirected. For more information, see Genymotion Desktop and VPN
Your GPU does not match Genymotion Desktop requirements
See Genymotion Desktop hardware requirements
You are using a laptop or notebook with a discrete and an integrated GPU (e.g. Intel/Nvidia or Intel/AMD)
Please, refer to How to configure NVIDIA Optimus and AMD Switchable Graphics for high performance with Genymotion Desktop (Windows)?
Genymotion Desktop has compatibility issues with Intel UHD/HD GPUs on Windows. For more details, see The virtual device crashes, freezes or fails to boot on Windows
Your display drivers are not up-to-date
Upgrade your display drivers to their latest stable version.
Nvidia open source drivers
Genymotion requires advanced OpenGL extensions which are not well supported by the open-source drivers "nouveau" for Nvidia GPUs. You need to use Nvidia proprietary drivers instead.
For more information, please refer to On Linux, the virtual device display is black/white/distorted